Randomized controlled trials have shown that lowering saturated fat intake may improve breast cancer survival.
Metastasis is the main cause of cancer-related deaths. Cancer is killed because it spreads. For example, the 5-year survival rate for women with local breast cancer is nearly 99%, but only 27% for women with metastatic cancer. However, despair is evident when there are papers such as “Our ability to effectively treat metastatic diseases has not changed significantly in the last few decades…” and “Targeting metastasis with snake toxins: Molecular mechanisms.”
We have built-in natural killing cells that roam our bodies, killing budding tumors. However, as I have discussed, a fat receptor called CD36 appears to be essential for cancer cells to spread, and these cancer cells respond to dietary fat intake, but not all fats.
CD36 is upregulated by palmitic acid in a way that helps to control cancer metastasis in diet, as shown below, with a 50-fold increase within 12 hours of consumption.
Palmitic acid is a saturated fat made from palm oil that can be found in junk foods, but is most concentrated in meat and dairy products. This may explain why there was no difference in the risk of breast cancer-specific death when looking at breast cancer mortality rates and dietary fats. The researchers say, “These meta-analyses show that saturated fat intake has a negative effect on breast cancer survival.”
This may also explain why “intake of high-fat dairy products, rather than low-fat dairy products, was associated with a higher risk of death after breast cancer diagnosis.” Skim milk could be even worse if dairy proteins like casein were a problem, but it wasn’t. It is saturated batal fat, possibly because it caused a mechanism to suppress cancer induced by CD36. Women who consumed more than one day serving of high-fat dairy products had a 50% higher risk of dying from breast cancer.
The same is seen in the relationship between dairy products and its survival of prostate cancer. The researchers said, “Drinking high-fat milk increased the risk of prostate cancer death by 600% in patients with local prostate cancer. Low-fat milk was not associated with such an increased risk.” Therefore, it appears to be animal fat rather than animal protein, and these findings are consistent with analysis of health professional follow-up studies (HPFS) and physician health studies (PHS) conducted by Harvard researchers.
There is further evidence that the fat receptor CD36 is involved. “Risk of colorectal cancer for meat consumption” increased from doubling to octope rings. This means that the chances of ingesting cancer for those carrying a certain type of CD36 gene have increased by eight times. So, “Is it time to give breast cancer patients a prescription for a low-fat diet?” It is essential to provide evidence-based guidelines, as cancer diagnosis is often referred to as a “teachable moment” when patients are motivated to make changes to their lifestyle. ”
In a randomized, prospective, multicenter clinical trial, the researchers said, “to test the effectiveness of dietary interventions designed to reduce fat intake in women with early stage breast cancer that have been excised.” As shown at 4:02 in my video, study participants in the dietary intervention group reduced from about 30% to 20% of their fat intake, reduced their saturated fat intake by about 40%, and maintained for 5 years. “After about five years of follow-up, women in the dietary intervention group had a 24% lower risk of recurrence” – 24% lower risk of cancer returning (24% lower risk of control group.”
That was Wins Study, a female intervention nutrition study. Later, there was a study on the Women’s Health Initiative, where again randomised women to reduce fat intake to 20% calories, “a dietary pattern randomised to a low-fat dietary pattern increased overall breast cancer survival. Furthermore, not only did breast cancer survival rates significantly increase, but women also experienced a decrease in heart disease and diabetes.
